May 21, 2024
Headlines

Crucible Therapeutics, a spinout of the University of Sheffield in England, has secured £5million (approximately $6.1 million) in funding to advance its development of genetherapies

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Gene therapies will be targeting neurodegenerative disorders associated with C9orf72gene mutations. The financing comes from investment firm Northern Gritstone and Europeanstartup studio Argobio Studio. These funds will support preclinical development andmanufacturing efforts aimed at preparing Crucible Therapeutics for its initial clinical trial. Thecompany’s focus is on addressing conditions such as motor neuron disease (MND), amyotrophiclateral…

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Navigate BioPharma, a subsidiary of Novartis, has recently announced a strategic collaboration with Becton Dickinson (BD)

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Collaboration aimed at advancing the development and commercialization of companion diagnostics and clinical decision-making tools utilizing flow cytometry technology. This partnership represents a significant step in the field of precisionmedicine and holds the potential to enhance the efficiency and accuracy of patient treatmentmatching.Through this collaborative effort, BD and Navigate BioPharma aim to offer comprehensivesolutions for…

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What is CAR-T cell therapy?

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CAR-T cell therapy, short for Chimeric Antigen Receptor T-cell therapy, is a revolutionary form ofimmunotherapy that has gained significant attention in recent years for its remarkable success intreating certain types of cancer, particularly blood cancers. This cutting-edge treatment involvesharnessing the power of the patient’s immune system to target and destroy cancer cells, offeringnew hope for…

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AstraZeneca and Daiichi’s breast cancer drug Shows Promise in Phase III BreastCancer Trial

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AstraZeneca’s Dato-DXd, an antibody drug conjugate, has shown promising results in a Phase IIIbreast cancer trial, known as TROPION-Breast01, conducted to assess its effectiveness inpatients with advanced HR-positive, HER2-low or -negative breast cancer. The trial revealed asignificant and clinically meaningful improvement in progression-free survival when comparedto chemotherapy chosen by investigators. AstraZeneca intends to share these…

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SCG Cell Therapy and A*STAR Collaborate to Establish Joint Laboratories for Cellular Immunotherapies

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SCG Cell Therapy (SCG) and the Agency for Science, Technology and Research (A*STAR) have unveiled a groundbreaking collaboration to establish joint laboratories focused on cellular immunotherapies. With a combined funding of nearly S$30 million under Singapore’s Research, Innovation and Enterprise 2025 Plan (RIE2025), this initiative aims to propel the development of induced pluripotent stem cell…

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What is companion diagnostics ?

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Companion diagnostics (CDx) refer to a type of medical test or diagnostic tool that is used to identify specific characteristics of a patient’s disease at themolecular or genetic level. These diagnostics are closely linked, or “companion,” to a particular medical treatment or therapy. The primary purpose of companion diagnostics is to assist healthcare professionals in…

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Illumina and Devyser Diagnostics Establish In Vitro Diagnostic Development Collaboration

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Devyser Diagnostics announced on Monday that it has forged an in vitro diagnostic development partnership with Illumina. This collaboration will empower Devyser, based in Sweden, to progress its next-generation sequencing-based in vitro diagnostic (IVD) tests on the Illumina MiSeqDx sequencer through the regulatory processes in both the United States and Europe. The specific financial and…

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Advancements in Gene Therapy: A Rapidly Evolving Frontier

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Gene therapy, a rapidly advancing field, seeks to enhance genes by rectifying mutations or making precise modifications for therapeutic purposes. Its primary goal is to improve genetic function by correcting mutations or performing site-specific modifications to address various medical conditions. The challenge lies in delivering therapeutic genes into stem cells, a critical process where molecular…

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Max Healthcare and ImmunoACT Team Up to Roll Out CAR-T Cell Therapy

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Max Healthcare has launched the cutting-edge Chimeric Antigen Receptor (CAR)-T Cell Therapy, a revolutionary treatment for specific cancers, now available at all its hospitals in Delhi-NCR. This innovative therapy involves genetically engineering patients’ immune cells, particularly T cells, in the laboratory to empower them in fighting cancer. The sourcing of CAR T cells for this…

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Overcoming TB Challenges: Targeted NGS for Comprehensive Resistance Detection

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In 2022, the World Health Organization (WHO) commissioned a series of systematic reviews, aiming to address the pressing need for expanded access to drug-resistance testing to combat the global tuberculosis (TB) epidemic. Currently, there are no WHO-recommended rapid diagnostics (WRDs) capable of detecting resistance to all drugs in the best available TB treatment regimens in…

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AIIMS-Bhubaneswar Elevates Cancer Care with Enhanced Precision Treatment Options

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AIIMS, Bhubaneswar has enhanced its cancer treatment capabilities by introducing High Energy Linear Accelerator (HELA) machines, inaugurated by Union Health Minister Mansukh Mandaviya. Priced at Rs 20 crore, the advanced HELA machine employs state-of-the-art technology to precisely identify cancer cells and deliver radiation therapy with pinpoint accuracy. This targeted approach ensures that only cancer-affected areas…

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HRD Evaluation: Testing Techniques, Scoring Mechanisms, and Integration in Clinical Practice

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Homologous Recombination Deficiency (HRD) testing involves assessing the genomic instability and the ability of cells to repair DNA through homologous recombination. Various testing methods, scoring systems, and integration strategies are employed in clinical practice. Here is an overview: HRD Testing Methods: 1. Genomic Sequencing:    – Next-Generation Sequencing (NGS): NGS technologies analyze the entire genome…

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Elevating Bladder Cancer Diagnosis: Liquid Biopsy and Protein Markers in Focus

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Bladder cancer diagnosis has undergone significant advancements, with liquid biopsy emerging as a promising non-invasive approach. This method utilizes urine samples to detect various biomarkers, providing valuable insights into cancer presence, progression, and treatment responses. Liquid biopsy in bladder cancer detection analyzes circulating tumor cells, cell-free DNA, RNA, and proteins in urine, offering a non-invasive…

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