Tempus has expanded its collaboration with Takeda to enhance oncology research and development using real-world data. As part of the new agreement, Takeda will leverage Tempus' multimodal datasets and biological modeling to advance its cancer therapeutics pipeline. Researchers from Takeda will access de-identified patient records through Tempus' Lens analytics platform, utilizing AI-powered tools to accelerate drug development insights.
Takeda's oncology pipeline includes antibody-drug conjugates, small molecules, bispecific antibodies, and gamma delta T-cell therapies. The two companies are also collaborating on a multiphase biological modeling project using a large repository of patient-derived tumor organoids. By genetically linking these organoid models to Tempus' multimodal dataset through DNA sequencing assays, the partnership aims to improve predictions of drug efficacy.
Currently, Tempus and Takeda are evaluating a panel of 60 organoids across 10 cancer types to test preclinical drug candidates. Tempus COO Ryan Fukushima highlighted the promising results of the collaboration, noting that it could accelerate Takeda’s oncology pipeline and contribute to the development of next-generation cancer treatments.