PathAI, a prominent figure in AI-powered pathology, has launched two groundbreaking AI products, PathExplore™ Immuno-Oncology Profiling (IOP) and IHC Explore1™, to empower cancer drug developers and clinical researchers with unprecedented insights. These innovations provide unparalleled single-cell and spatial resolution of the tumor microenvironment from routine pathology samples, facilitating biomarker discovery and enhancing understanding of treatment response for the next generation of cancer therapeutics.
PathExplore IOP accelerates the characterization of immune phenotypes crucial for identifying tumors likely to respond to immunotherapy. By quantifying tumor infiltrating lymphocytes (TILs) and their spatial distribution using routine hematoxylin and eosin (H&E) samples, researchers can gain insights into immune inflamed, desert, or excluded characteristics, ultimately leading to improved patient survival. PathExplore IOP’s AI-powered approach offers highly accurate and efficient immune phenotype classification, enabling researchers to inform biomarker strategies for patient stratification and mechanisms of response and resistance.
On the other hand, IHC Explore™ addresses the need for spatial quantification of IHC biomarkers in single-cell resolution with broad target compatibility. This product streamlines the process of defining optimal scoring systems for novel IHC assays, which is crucial in early stage biomarker development. By providing standardized features that quantify IHC stain abundance within and around cells of the tumor microenvironment, IHC Explore enables drug developers to build biomarker scoring strategies and identify patients most responsive to treatment. PathAI’s partnership with Roche further facilitates the translation of AI insights and scoring strategies into companion diagnostic development.
These advancements mark a significant step forward in AI-powered pathology, offering researchers and clinicians the tools they need to make meaningful advancements in cancer research, treatment, and care. With their commitment to providing accurate biological insights and improving patient outcomes, PathAI continues to lead the way in precision pathology, supporting laboratories, research institutions, and the biopharma industry in their transition to digital workflows and accelerating drug development for complex diseases.