Mankind Pharma Limited, one of India’s largest pharmaceutical companies, has partnered with Innovent Biologics, a leading biopharmaceutical firm, to exclusively license and commercialize sintilimab, a cutting-edge PD-1 immunotherapy, in the Indian market. This collaboration aims to address the growing cancer burden in India and enhance access to innovative treatments.
Cancer is a critical health challenge in India, with its impact projected to reach 29.8 million DALYs by 2025, according to The National Cancer Registry Programme. Sintilimab, marketed as Tyvyt in China, is a high-quality PD-1 monoclonal antibody developed by Innovent and Eli Lilly. By blocking the PD-1/PD-L1 pathway, it reactivates T-cells, enabling the immune system to combat cancer more effectively. Approved in China for eight cancer types, including lung, liver, and gastric cancers, Tyvyt has demonstrated exceptional efficacy and safety, benefiting millions since its launch in 2018.
Under this agreement, Mankind Pharma will manage the registration, import, marketing, sales, and distribution of sintilimab in India, while Innovent will oversee manufacturing and supply. This ensures high-quality standards and product availability. Innovent will receive upfront, regulatory, and milestone payments as part of the deal.
Mankind Pharma’s vast distribution network, comprising over 13,000 stockists and 16,000+ field personnel, will ensure widespread accessibility across urban and rural India. This partnership reflects a shared commitment to transforming cancer care by introducing advanced, affordable treatments.
“At Mankind Pharma, we are dedicated to improving patient outcomes and reshaping oncology care in India,” stated Atish Majumdar, Senior President of Sales & Marketing. Dr. Samuel Zhang, Chief Business Officer of Innovent, emphasized the importance of this collaboration in bringing hope to cancer patients by leveraging Mankind’s extensive expertise and network.