Bruker Corporation has made a strategic minority investment in NovAliX, a preclinical Contract Research Organization (CRO) specializing in drug discovery services, headquartered in Strasbourg, France. This investment aims to accelerate NovAliX's growth and expand its presence in Europe and the United States.
The collaboration between Bruker and NovAliX will focus on advancing drug discovery technologies, particularly in functional structural biology and biophysical methods for studying molecular dynamics, drug interactions, and therapeutic mechanisms of action. Leveraging Bruker’s advanced biophysical tools, such as NMR, mass spectrometry, and single-cell biology techniques, NovAliX will enhance its drug discovery services, from target assessment to lead optimization.
Joint innovation efforts will include NMR studies on protein and RNA structures, X-ray crystallography for structure-guided drug discovery, and high-throughput SPR for kinetics and binding studies. The partnership will also explore novel therapeutic peptides and oligonucleotides, as well as unique research on intrinsically disordered proteins for condensate biology.
Looking ahead, Bruker and NovAliX plan to establish the Biophysics Institute for Biomedical Research (IBRB) in Strasbourg by 2026. This institute will foster collaboration between biotechs, start-ups, and academic groups, driving innovation in biophysics and drug discovery.
Stephan Jenn, President of NovAliX, emphasized that the partnership will strengthen their leadership in biophysics and drug discovery, while Dr. Falko Busse, President of Bruker BioSpin Group, highlighted the potential to support the discovery of new medicines through advanced biophysical tools.
Financial details of the investment were not disclosed. NovAliX has over 430 employees across its European R&D and CRO service sites, and is expanding its reach in the U.S. and Japan.