Novo Nordisk has acquired 2seventy bio's hemophilia A program and the rights to its in vivo gene editing technology in a deal valued at up to $40 million. Initially partners since 2019 on a gene editing therapy for hemophilia A, the new agreement sees 2seventy transferring this program to Novo Nordisk, effectively ending their prior collaboration. Employees from 2seventy dedicated to the hemophilia A initiative will now continue their work under Novo Nordisk's leadership.
In addition to the hemophilia A program, 2seventy will transfer its megaTAL gene editing technology to Novo Nordisk. This technology will be utilized beyond oncology and gene editing for autologous or allogeneic cell therapies of immune cells in autoimmune disease treatment. Novo Nordisk also gains a license to associated intellectual property.
The asset purchase aligns with 2seventy's recent business restructuring efforts, which included a 40% reduction in workforce to streamline operations and focus resources. This strategic move allows 2seventy to prioritize advancing Abecma (idecabtagene vicleucel), its BCMA-directed CAR T-cell therapy for multiple myeloma, in partnership with Bristol Myers Squibb.
2seventy's CEO, Chip Baird, expressed confidence in Novo Nordisk's ability to advance the hemophilia A treatment and highlighted that the divestiture supports their commitment to maximizing Abecma's impact.
For Novo Nordisk, the acquisition expands their genome editing capabilities and enables the utilization of megaTAL technology in novel therapeutic applications. Karina Thorn, corporate VP at Novo Nordisk, emphasized the strategic importance of this deal in broadening their technological portfolio.