Datar Cancer Genetics (DCG) has launched Exacta AI, an advanced AI-driven platform designed to provide optimized treatment options for cancer patients who have exhausted standard therapies. This next-generation multi-analyte system integrates a 360° tumor work-up with AI-assisted analysis, decoding complex tumor interactome data—including molecular (NGS: DNA+RNA), proteomic, genomic, functional, and clinical insights—to deliver personalized treatment recommendations with thorough risk-benefit analysis.
Exacta AI processes real-time wet lab data and integrates it with vast knowledge sources to assess drug synergy, interactions, toxicity, and contraindications across various treatment modalities, including Antibody-Drug Conjugates (ADCs), Checkpoint Inhibitors (CPIs), targeted therapies, endocrine agents, chemotherapy, and repurposed drugs. It can recommend up to 10 evidence-based multi-drug combinations for oncologists and molecular tumor boards (MTBs), offering hope to refractory or recurrent cancer patients.
Speaking at the Datar Advisory Board Meeting in Mumbai, Dr. Sewanti Limaye, Director of Medical and Precision Oncology at Sir HN Reliance Foundation Hospital, highlighted the AI-driven approach as a game-changer in structuring and analyzing multi-analyte data. Dr. Andy Gaya, Clinical Oncologist at Cromwell Hospital, London, called Exacta AI a paradigm shift in tumor analysis, improving therapy selection while reducing ineffective treatments.
Dr. Darshana Patil, Senior Director – Global Strategy and Medical Affairs, emphasized its role in transforming vast clinical data into actionable insights for oncologists and MTBs. Dr. Vineet Datta, Senior Director – Global Strategy and Business Development, noted its ability to function like a team of multidisciplinary experts, delivering precision-driven treatment recommendations in minutes.
In a retrospective in-silico study of 265 patients with drug-resistant cancers, Exacta AI generated 7-10 therapy options for 100% of cases, compared to conventional molecular profiling, which identified a maximum of two options for only 15% of patients. Available for seamless integration in cancer centers and hospitals, Exacta AI ensures continuous training, support, and updates.