President Droupadi Murmu is poised to inaugurate India’s groundbreaking CAR T-Cell therapy for advanced blood cancer treatment at the Indian Institute of Technology (IIT) Bombay, Powai campus on April 4. This milestone offers hope to Indian patients by providing the therapy at a significantly reduced cost of ₹40 lakh, a stark contrast to the exorbitant ₹5 crore expense in the US, making it accessible to many.
CAR T-Cell therapy, a personalized treatment, differs from chemotherapy as it is tailored to individual patients. Spearheaded by Dr. Gaurav Narula, a pediatric hematologist-oncologist at Tata Hospital, and Dr. Rahul Purwar, a faculty member at IIT-Bombay, Powai, the initiative introduces a novel CAR T-Cell therapy capable of prolonged circulation within the body. This innovative approach holds the promise of long-term cancer remission without requiring a bone marrow transplant.
In this therapy, the patient’s blood is utilized to isolate T-cells, which are then genetically modified in the lab to produce cancer-fighting cells called CAR-T cells expressing chimeric antigen receptors (CARs) specific to cancer cells. These modified cells are reintroduced into the patient, designed to seek out and eliminate cancer cells in the body.