Tempus AI, Inc. (NASDAQ: TEM), a leader in artificial intelligence and precision medicine, announced its multimodal immune profile score (IPS) algorithmic test is now available for research use only (RUO). As the first in Tempus' immunotherapy-based portfolio, IPS uses DNA and RNA test results to calculate a score from 0-100, classifying patients as IPS-Low or IPS-High. This pan-cancer laboratory-developed test (LDT) helps identify patients likely to respond to immunotherapy. Available to life sciences partners, IPS will be an add-on option for clinicians ordering Tempus’ xT and xR tests by year-end. Tempus is conducting a retrospective study to evaluate IPS's utility in advanced pan-cancer patients treated with immune checkpoint inhibitors (ICI), with results expected later this year.
Tempus has also licensed a machine-learning-based test from Dr. Timothy A. Chan of Cleveland Clinic, which predicts the efficacy of immune checkpoint blockade using patient-specific data. This test complements Tempus' growing portfolio of immunotherapy biomarkers.
"Immune checkpoint inhibitors have a significant impact on patient outcomes. Our IPS test is the first multimodal algorithm in immunotherapy, offering critical insights for patient care," said Halla Nimeiri, MD, Chief Development Officer at Tempus. Dr. Chan added, "Collaborating with Tempus allows us to develop AI-powered models to identify patients who may benefit from cancer immunotherapies."
Tempus’ AI platform supports personalized treatment selection, joining other tests like HRD, TO, DPYD, and PurISTSM. Tempus aims to provide physicians with tools that continuously learn from collected data, advancing precision medicine. For more information, visit tempus.com/contact-us.