Redcliffe Labs, a research-oriented omnichannel diagnostics service provider operating across India, has conducted a study revealing chromosome polymorphism (CPM) as a significant contributor to recurrent pregnancy loss. Led by Dr. Ashish Fauzdar, the study analyzed 1,400 individuals, including 700 couples diagnosed with recurrent pregnancy loss.
In India, recurrent pregnancy loss poses a considerable burden, with approximately 7.4% reported cases, according to government data. Despite thorough assessments, many cases remain unexplained. Traditionally, chromosome polymorphisms were considered benign variants. However, Redcliffe Labs’ study marks a paradigm shift, indicating a notably higher prevalence of CPM, around 33.7%, among couples experiencing repeated pregnancy loss and infertility.
Dr. Ashish Fauzdar, Head of Clinical Genomics & Cytogenetics at Redcliffe Labs, emphasized the groundbreaking nature of their findings. He underscored the significance of CPM, suggesting it plays a more substantial role in recurrent pregnancy losses than previously understood. While acknowledging the need for further research, Dr. Fauzdar highlighted the practical implications of their discovery. It provides crucial insights for doctors to counsel patients and implement timely clinical interventions for couples planning future pregnancies following unexplained recurrent pregnancy loss.
The researchers caution that while their findings are enlightening, careful interpretation is warranted, and additional robust evidence is imperative. Patients should receive personalized counseling, considering the role of chromosomal polymorphism in the prognosis and management of unexplained recurrent pregnancy loss.